Eyconis is developing novel therapies to transform the lives of patients with eye disease.
There is a high unmet need for improved ophthalmology therapeutics particularly in wet age-related macular degeneration (AMD), diabetic macular edema (DME), retinal vein occlusion (RVO) and geographic atrophy (GA). We have the potential to be the first to achieve long-acting and effective delivery of multiple clinically validated and emerging medicines - which together constitute the most used therapies for the major causes of blindness.
With the expertise of the Eyconis team and exclusive, worldwide license to TransCon technology for ophthalmology from Ascendis Pharma (NASDAQ: ASND), we believe Eyconis is well-positioned to develop transformational, best-in-class therapies for eye disease that will create significant value for patients, stakeholders, and society.
Dr. Mark Bachleda joined Eyconis, Inc. as Chief Executive Officer and Board Director in June 2024.
Dr. Bachleda has served in executive leadership roles at Amgen, Juno Therapeutics, and Bristol Myers Squibb (BMS), and most recently he was Chief Commercial Officer at Galera Therapeutics. Prior to joining Galera, he served as Vice President & U.S. Business Unit Head of the CAR T cell therapy franchise at BMS, a role he held previously at Celgene Corporation before its acquisition by BMS for $74 billion in 2019. Prior to this, he was Vice President, Sales & Account Management at Juno when it was acquired by Celgene for $9 billion in 2018. Previously, he had a 15-year career at Amgen in U.S. and international roles of increasing responsibility up to Country President & General Manager of Amgen Czech Republic. Earlier in his career, he held positions at Pfizer, Inc., and Johnson & Johnson. Dr. Bachleda is a registered pharmacist and received his PharmD degree from the University of Illinois at Chicago. He completed a post-doctoral fellowship in health policy and economics at Thomas Jefferson University and earned MBA degrees from both Columbia University and the University of California, Berkeley.
Dr. Emmett Cunningham, co-founded Eyconis, Inc., a spinout of Ascendis Pharma (NASDAQ; ASND), in 2023 and has served as Executive Chair since inception.
Dr. Emmett Cunningham has been a full-time entrepreneur and investor for more than 20 years. Dr. Cunningham joined HealthQuest Capital Management as a Senior Partner in 2023. Prior to 2023, he served as a Senior Managing Director at Blackstone Life Sciences group (BXLS) of Blackstone, Inc. (BX), joining that company through the acquisition of Clarus Ventures in 2018, where he was a member of the full-time investment team since that firm’s inception in 2006. Emmett has led or co-led investments in medical technology and biotechnology that have supported FDA approval for ten therapeutics with one additional therapeutic pending FDA submission. Prior to investing, his previous roles included Senior Vice President, Medical Strategy at Eyetech Pharmaceuticals, Inc., where he was a key member of the leadership team responsible for the development of Macugen® (pegaptanib sodium), a pioneering, first-in-class VEGF-A inhibitor for the treatment of age-related macular degeneration and diabetic macular edema. Emmett's extensive experience and leadership have been recognized further through his role as the founder and chairman of the Ophthalmology Innovation Summit (OIS) symposium for more than a decade.
Emmett currently serves on the Board of Galera Therapeutics and Nacuity Pharmaceuticals, and previously held positions on the boards of SARcode Biosciences (acquired by Shire), Neomend (acquired by Bard), Restoration Robotics (acquired by Venus Concept), Annexon Biosciences (ANNX), GrayBug Vision (GRAY), Lumos Pharma (LUMO), SFJ Pharmaceutical Group, Viewpoint Therapeutics, and Silktech Biopharmaceuticals. Additionally, he has played instrumental roles as a co-founder and personal seed investor in several companies, including Xeris Biopharma Holdings (XERS), Aiolos Bio (acquired by GSK), Placid0 (acquired by WALDO), and Pr3vent Medical. He serves as Innovator in Residence for Johns Hopkins Technology Ventures (JHTV); as a member of the Biomedical Engineering Advisory Board at Johns Hopkins University; is an advisor to the Byers Center for BioDesign at Stanford University. Emmett’s dedication to philanthropic endeavors is evident through his service on the Boards of The Alta Foundation and EverythingALS, contributing to meaningful unmet needs within the healthcare community.
Emmett earned his MD and MPH in epidemiology and statistics from Johns Hopkins University and holds a PhD in neuroscience from the University of California at San Diego for research conducted at The Salk Institute. He completed residency in ophthalmology and fellowship training in Corneal Disease and Uveitis at UCSF and The Francis I. Proctor Foundation, a medical retina and uveitis fellowship at Moorfields Eye Hospital in London, and a fellowship in public health ophthalmology with Prof. Alfred Sommer at the Wilmer Eye Institute in Baltimore. In addition to his professional commitments, Emmett is actively involved in teaching and holds positions as an Adjunct Clinical Professor of Ophthalmology at California Pacific Medical Center and Stanford University, as well as a Research Associate at The Francis I. Proctor Foundation, UCSF School of Medicine. He has co-authored over 400 papers related to his clinical and research efforts.
Oliver Stauch, PhD, is a highly accomplished pharmaceutical executive with over two decades of experience in the industry. He is currently the Chief Operating Officer and a founding member of Eyconis. Before Eyconis, he held significant roles at Ascendis Pharma, including Head of Ophthalmology. Dr. Stauch’s career includes leadership positions at Genentech, Chugai Japan, and Roche Pharmaceuticals Switzerland. At Roche, he notably contributed to the development of pioneering drug delivery innovations for therapies like Actemra™, Herceptin Hylecta™, and Rituxan Hycela™. Additionally, he has served on the Advisory Board for Atropos Therapeutics, a biotech company specializing in anti-aging treatments. His educational background includes a PhD in Industrial Pharmacy from the University of Freiburg, Germany, a Master’s in Pharmaceutical Sciences from the University of Innsbruck, Austria, and executive training from Stanford University and London Business School.
Rolf Jansen is a pharmaceutical executive with over thirty years of experience in the industry. A chemical engineer trained at the University of Massachusetts, Amherst, Rolf has played pivotal roles in the design, development, and commercialization of successful controlled release products including Duragesic®, Ionsys™, and Liletta®. He has held product development leadership positions at companies including Ascendis, Relypsa, Johnson & Johnson, and Alza. Rolf is known for his innovative thinking, personnel development orientation, and collaborative leadership style. Passionate about improving patient outcomes, Rolf is dedicated to advancing new and novel therapies.
YongQi Mu, PhD joined Eyconis in March 2024, bringing over 25 years of experience from discovery to late-stage development. Previously, she was a Senior Director at Ascendis, leading chemical development and manufacturing for TransCon projects. At Theravance and Vifor/Relypsa, she played key roles in the discovery of Vibativ®, Yupelri®, and the development of Veltassa®. YongQi is a co-inventor and author of over 100 patent applications and journal publications. She completed her postdoctoral training at Stanford University, earned a PhD in Medicinal Chemistry from Wayne State University, an MS from the Chinese Academy of Medical Science, and a BS from Beijing Normal University.
Chris Heynes is a seasoned technical leader with over 30 years of experience in the pharmaceutical industry. With a background in biochemistry and cell biology from UC San Diego, Chris has a proven track record in designing, developing, and implementing innovative processes and equipment for the production of complex therapeutic, diagnostic, and drug delivery products. He has navigated and supported products through technical and regulatory challenges, from initial bench batches to commercial production of blockbuster products with complex supply chains across global organizations. Prior to Eyconis, Chris worked most recently at Ascendis and Genentech, focused on technical leadership.
William Galush, PhD, is an accomplished scientist and leader with extensive experience in drug development. He specializes in analytical and formulation development across large and small molecule formats, including sustained-release systems. Dr. Galush has held key technical, management, and cross-functional leadership roles at Ascendis Pharma, Achaogen, and Genentech. A biophysical chemist by training, he earned his Phd in Chemistry from UC Berkeley and has published numerous papers. An area of passion for him is making multi-disciplinary connections inside and outside of professional life to tackle complex challenges.
Dr. Emmett Cunningham, co-founded Eyconis, Inc., a spinout of Ascendis Pharma (NASDAQ; ASND), in 2023 and has served as Executive Chair since inception.
Dr. Emmett Cunningham has been a full-time entrepreneur and investor for more than 20 years. Dr. Cunningham joined HealthQuest Capital Management as a Senior Partner in 2023. Prior to 2023, he served as a Senior Managing Director at Blackstone Life Sciences group (BXLS) of Blackstone, Inc. (BX), joining that company through the acquisition of Clarus Ventures in 2018, where he was a member of the full-time investment team since that firm’s inception in 2006. Emmett has led or co-led investments in medical technology and biotechnology that have supported FDA approval for ten therapeutics with one additional therapeutic pending FDA submission. Prior to investing, his previous roles included Senior Vice President, Medical Strategy at Eyetech Pharmaceuticals, Inc., where he was a key member of the leadership team responsible for the development of Macugen® (pegaptanib sodium), a pioneering, first-in-class VEGF-A inhibitor for the treatment of age-related macular degeneration and diabetic macular edema. Emmett's extensive experience and leadership have been recognized further through his role as the founder and chairman of the Ophthalmology Innovation Summit (OIS) symposium for more than a decade.
Emmett currently serves on the Board of Galera Therapeutics and Nacuity Pharmaceuticals, and previously held positions on the boards of SARcode Biosciences (acquired by Shire), Neomend (acquired by Bard), Restoration Robotics (acquired by Venus Concept), Annexon Biosciences (ANNX), GrayBug Vision (GRAY), Lumos Pharma (LUMO), SFJ Pharmaceutical Group, Viewpoint Therapeutics, and Silktech Biopharmaceuticals. Additionally, he has played instrumental roles as a co-founder and personal seed investor in several companies, including Xeris Biopharma Holdings (XERS), Aiolos Bio (acquired by GSK), Placid0 (acquired by WALDO), and Pr3vent Medical. He serves as Innovator in Residence for Johns Hopkins Technology Ventures (JHTV); as a member of the Biomedical Engineering Advisory Board at Johns Hopkins University; is an advisor to the Byers Center for BioDesign at Stanford University. Emmett’s dedication to philanthropic endeavors is evident through his service on the Boards of The Alta Foundation and EverythingALS, contributing to meaningful unmet needs within the healthcare community.
Emmett earned his MD and MPH in epidemiology and statistics from Johns Hopkins University and holds a PhD in neuroscience from the University of California at San Diego for research conducted at The Salk Institute. He completed residency in ophthalmology and fellowship training in Corneal Disease and Uveitis at UCSF and The Francis I. Proctor Foundation, a medical retina and uveitis fellowship at Moorfields Eye Hospital in London, and a fellowship in public health ophthalmology with Prof. Alfred Sommer at the Wilmer Eye Institute in Baltimore. In addition to his professional commitments, Emmett is actively involved in teaching and holds positions as an Adjunct Clinical Professor of Ophthalmology at California Pacific Medical Center and Stanford University, as well as a Research Associate at The Francis I. Proctor Foundation, UCSF School of Medicine. He has co-authored over 400 papers related to his clinical and research efforts.
Dan Estes is a General Partner with Frazier Life Sciences, a healthcare investment firm focused on creating and investing in biopharmaceutical companies developing novel therapeutics. He focuses on early-stage private investments including company formation and has led Frazier Life Sciences’ investments in companies such as Arcutis (ARQT), Lengo (M&A by Blueprint), Sierra Oncology (M&A by GSK), Tarsus (TARS), Semnur (M&A by Scilex), Radionetics, Sudo Bio, Bluejay, and Hummingbird. He has also been involved with Frazier Life Sciences’ investments in Acerta (M&A by AZ), Vaxcyte (PCVX), Ignyta (M&A by Roche), Tobira (M&A by Allergan), and Precision Dermatology (M&A by Valeant). Prior to joining Frazier Life Sciences, Dan was a management consultant with McKinsey & Company’s global pharmaceuticals practice. He received his PhD in Biomedical Engineering from the University of Michigan and holds a BS in Electrical Engineering from Stanford University.
Jan Møller Mikkelsen founded Ascendis Pharma in 2007 and has served as President and Chief Executive Officer, as well as Board member since then. From 2002 to 2006, Mr. Mikkelsen was President and Chief Executive Officer of LifeCycle Pharma A/S (now Veloxis Pharmaceuticals A/S). From 2000 to 2002, Mr. Mikkelsen was President of the Pharmaceutical Division of Maxygen, Inc. Prior to that, Mr. Mikkelsen co-founded ProFound Pharma A/S (a biopharmaceutical company acquired by Maxygen, Inc.), where he served as Co-Chief Executive Officer from 1999 to 2000. From 1988 to 1999, Mr. Mikkelsen held various positions at Novo Nordisk A/S, a global healthcare company, including Vice President of Protein Discovery. In late 2021, Mr. Mikkelsen was named Chairman of the Board of Directors of Hummingbird Bioscience, a clinical-stage biotechnology company focused on cancer and autoimmune disease. He received a Cand. Scient. degree in Biochemistry from the University of Odense, Denmark and pursued his post-doctoral research at Children’s Hospital Oakland in Oakland, California, U.S.
Anna is a Principal at Frazier Life Sciences, where she focuses on private investments and company creation. She co-led Frazier’s investments in and currently serves on the boards of Eyconis and Blue Water Bio. She is currently a board observer at Inipharm, Attovia Therapeutics, Architect Therapeutics, and Diagonal Therapeutics. Anna has also been involved in Frazier’s investments in Amunix Pharmaceuticals (acquired by Sanofi), Lengo Therapeutics (acquired by Blueprint Medicines), SanReno Therapeutics (acquired by Novartis), and HilleVax (NASDAQ: HLVX).
Prior to joining Frazier, Anna was a management consultant in L.E.K. Consulting’s life sciences practice and an entrepreneurial fellow at Flagship Pioneering. Anna received her PhD in Systems Biology from Harvard University, where she was a National Science Foundation Graduate Research Fellow. Anna also holds an AB in Biochemical Sciences from Harvard College.
Yvonne Yamanaka, PhD, is a Principal at venBio Partners with a background in biological engineering and life science company creation. Prior to joining venBio, Yvonne was a member of the venture creation team at Flagship Pioneering. She began her research career leading the development of a novel immunotherapy technology at EMD/Merck Serono. Yvonne received her PhD in Biological Engineering from MIT, where she was a Siebel Scholar and NSF Graduate Research Fellow, and her BSE in Biomedical Engineering from Duke University, where she was an Angier B. Duke and Goldwater scholar.
Conrad joined HealthQuest in 2023 as a Partner focused on the Tactical Opportunities Fund. Conrad has nearly two decades of healthcare investing experience, ranging from seed investing and company formation to structured growth capital for commercial stage companies. He has been an investor at OrbiMed, Healthcare Royalty Partners, and Three Arch Partners. He has also led corporate development teams at Medtronic. Conrad earned his BS from MIT, MD from the Harvard-MIT Division of Health Sciences and Technology (HST) at Harvard Medical School, and MBA from Harvard Business School.
Aaron Royston, MD, MBA is a Managing Partner at venBio with a background in life science investing, healthcare strategy, and as an entrepreneur. He has helped to launch, invest, and serve on the board of a number of biotech companies including Apellis Pharmaceuticals (IPO 2017), Menlo Therapeutics (IPO 2018), Akero Therapeutics (IPO 2019), Harmony Biosciences (IPO 2020), Ventyx BioSciences (IPO 2021), RayzeBio (IPO 2023, acquired by Bristol Myers Squibb), Ablaze Pharmaceuticals, 35Pharma, and Attovia Therapeutics. These companies have developed six FDA-approved treatments that are now available to patients with conditions ranging from rare, genetic diseases to the most common form of age-related blindness.
Prior to joining venBio, Dr. Royston was a member of the investment team at Vivo Capital, a life science venture capital firm. Previously, he worked at Bain & Company, where he advised biotechnology companies on a range of strategic and operational issues. Earlier in his career, he coordinated clinical research at Mount Sinai Medical Center, where his research has been published and presented in multiple medical journals and conferences. Dr. Royston received his BS in biological sciences from Duke University, and his MD, and MBA degrees from the University of Pennsylvania.
Dr. Mark Bachleda joined Eyconis, Inc. as Chief Executive Officer and Board Director in June 2024.
Dr. Bachleda has served in executive leadership roles at Amgen, Juno Therapeutics, and Bristol Myers Squibb (BMS), and most recently he was Chief Commercial Officer at Galera Therapeutics. Prior to joining Galera, he served as Vice President & U.S. Business Unit Head of the CAR T cell therapy franchise at BMS, a role he held previously at Celgene Corporation before its acquisition by BMS for $74 billion in 2019. Prior to this, he was Vice President, Sales & Account Management at Juno when it was acquired by Celgene for $9 billion in 2018. Previously, he had a 15-year career at Amgen in U.S. and international roles of increasing responsibility up to Country President & General Manager of Amgen Czech Republic. Earlier in his career, he held positions at Pfizer, Inc., and Johnson & Johnson. Dr. Bachleda is a registered pharmacist and received his PharmD degree from the University of Illinois at Chicago. He completed a post-doctoral fellowship in health policy and economics at Thomas Jefferson University and earned MBA degrees from both Columbia University and the University of California, Berkeley.
If you are passionate about joining a team dedicated to delivering new therapeutic solutions to patients, please check the job openings link for our current opportunities.
General information: info@eyconis.com
Eyconis Inc.
1200 Bridge Parkway, Suite 200
Redwood City, CA 94065